As the use of GLP-1 medications like Ozempic and Wegovy continues to climb, many patients are turning to dietary supplements to manage side effects. This shift toward using dietary supplements is driven by a need to mitigate symptoms such as nausea, fatigue, and gastrointestinal distress.

Why are people seeking supplements?

While GLP-1 drugs are effective for treating obesity and type 2 diabetes, they often come with physical challenges. Some users report experiencing brittle nails, weakness, and constipation. To counter these issues, individuals are purchasing various products, including:

  • Fiber and electrolytes
  • Collagen
  • Magnesium and B12

For some, these regimens can cost between $110 and $300 every month. Because these costs are typically not covered by insurance, some users have turned to social media to earn income through brand partnerships.

What are the regulatory concerns?

Medical professionals and regulators are raising alarms regarding the lack of oversight in the supplement industry. Unlike prescription medications, vitamins and dietary supplements do not require preapproval by the U.S. Food and Drug Administration. This makes it difficult for consumers to verify the scientific credibility of a product.

Furthermore, the influence of social media has complicated the landscape. Companies can utilize influencers to promote products, sometimes making unverified claims. Rob Fried, CEO of Niagen Bioscience, noted that companies can hire hundreds of creators on platforms like TikTok "to make whatever claims will sell."

What to watch next

With JPMorgan research suggesting the number of Americans using GLP-1 drugs could rise from 10 million to 25 million by 2030, the demand for these products will likely increase. Regulators are currently considering new rules to govern how supplements are marketed online to ensure consumer safety.

FAQ

Do supplements require FDA approval?

No, vitamins and dietary supplements do not need to be preapproved by the FDA before they are sold.

Why are GLP-1 users buying supplements?

Users often use them to help ease side effects like nausea, weakness, and gastrointestinal issues caused by the medication.